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Article

Integrin αPS3/βν-mediated phagocytosis of apoptotic cells and bacteria in Drosophila.

The Journal of biological chemistry - 12 Apr 2013

Nonaka Saori, Nagaosa Kaz, Mori Toshinobu, Shiratsuchi Akiko, Nakanishi Yoshinobu

Abstract excerpt

Integrins exert a variety of cellular functions as heterodimers of two transmembrane subunits named α and β. Integrin βν, a β-subunit of Drosophila integrin, is involved in the phagocytosis of apoptotic cells and bacteria. Here, we searched for an α-subunit that forms a complex and cooperates with βν. Examinations of RNAi-treated animals suggested that αPS3, but not any of four other α-subunits, is required for...

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Identifiers

PMID: 23426364
DOI: 10.1074/jbc.M113.451427
PMCID: PMC3624420

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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