Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Requirements for integrins during Drosophila development.

Development (Cambridge, England) - 1 Mar 1990

Zusman S, Patel-King R S, Ffrench-Constant C, Hynes R O

Abstract excerpt

The common beta subunit of the PS antigens of Drosophila is homologous with vertebrate integrins and is encoded by the lethal(1)myospheroid gene. We have generated flies mosaic for wild-type and mutant alleles of lethal(1)myospheroid using adult gynandromorphs and radiation-induced somatic crossing over. The defects observed in the gynandromorphs demonstrate widespread requirements for PS integrins during...

Topics

Animals
Blotting, Northern
Drosophila
Embryo, Nonmammalian
Eye
Gene Expression
Genes, Lethal
Immunohistochemistry
Integrins
Mosaicism
Mutation
Photoreceptor Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Wings, Animal

Source

Identifiers

PMID: 2340808
DOI: 10.1242/dev.108.3.391

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2340808-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Requirements for integrins during Drosophila development.PMID 2340808Read ↗

Integrins and morphogenesis.Semantic proximity Read ↗

Analyses of PS integrin functions during Drosophila development.Semantic proximity Read ↗

Functions for PS integrins in tissue adhesion, migration, and shape changes during early embryonic development in Drosophila.Semantic proximity Read ↗

Requirements for the cytoplasmic domain of the alphaPS1, alphaPS2 and betaPS integrin subunits during Drosophila development.Semantic proximity Read ↗

PS2 integrin requirements in Drosophila embryo and wing morphogenesis.Semantic proximity Read ↗

Genetic analysis of the Drosophila PS integrins.Semantic proximity Read ↗

Functions of the cytoplasmic domain of the beta PS integrin subunit during Drosophila development.Semantic proximity Read ↗

Integrins as mediators of morphogenesis in Drosophila.Semantic proximity Read ↗

Genetic interactions with integrins during wing morphogenesis in Drosophila.Semantic proximity Read ↗

Autosomal mutations affecting adhesion between wing surfaces in Drosophila melanogaster.Semantic proximity Read ↗

Null mutations in the alpha PS2 and beta PS integrin subunit genes have distinct phenotypes.Semantic proximity Read ↗

Disruption of C-terminal cytoplasmic domain of betaPS integrin subunit has dominant negative properties in developing Drosophila.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.