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Article

Identification of cytoskeletal regulatory proteins required for efficient phagocytosis in Drosophila.

Microbes and infection - 1 Aug 2003

Pearson Alan M, Baksa Katalin, Rämet Mika, Protas Meredith, McKee Mary, Brown Dennis, Ezekowitz R Alan B

Abstract excerpt

Phagocytosis is a complex and apparently evolutionarily conserved process that plays a central role in the immune response to infection. By ultrastructural and functional criteria, Drosophila hemocyte (macrophage) phagocytosis resembles mammalian phagocytosis. Using a non-saturated forward genetic screen for larval hemocyte phagocytosis mutants, D-SCAR and profilin were identified as important regulators of...

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PMID: 12919849
DOI: 10.1016/s1286-4579(03)00157-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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