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Article

Exploring the structure and function of Thermotoga maritima CorA reveals the mechanism of gating and ion selectivity in Co2+/Mg2+ transport.

The Biochemical journal - 1 May 2013

Nordin Nurhuda, Guskov Albert, Phua Terri, Sahaf Newsha, Xia Yu, Lu Siyan, Eshaghi Hojjat, Eshaghi Said

Abstract excerpt

The CorA family of divalent cation transporters utilizes Mg2+ and Co2+ as primary substrates. The molecular mechanism of its function, including ion selectivity and gating, has not been fully characterized. Recently we reported a new structure of a CorA homologue from Methanocaldococcus jannaschii, which provided novel structural details that offered the conception of a unique gating mechanism involving...

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Identifiers

PMID: 23425532
DOI: 10.1042/BJ20121745
PMCID: PMC3629940

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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