Article
The CorA Mg2+ channel is required for the virulence of Salmonella enterica serovar typhimurium.
Journal of bacteriology - 1 Oct 2008
Papp-Wallace Krisztina M, Nartea Margaret, Kehres David G, Porwollik Steffen, McClelland Michael, Libby Stephen J, Fang Ferric C, Maguire Michael E
Abstract excerpt
CorA is the primary Mg(2+) channel in Salmonella enterica serovar Typhimurium. A corA mutant is attenuated in mice and defective for invasion of and replication within epithelial cells. Microarray studies show that several virulence effectors are repressed in a corA mutant strain, which ultimately manifests itself as a decrease in virulence.
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