Article
Right-sided rhabdoid colorectal tumors might be related to the serrated pathway.
Diagnostic pathology - 20 Feb 2013
Pancione Massimo, Remo Andrea, Sabatino Lina, Zanella Caterina, Votino Carolina, Fucci Alessandra, Di Blasi Arturo, Lepore Giovanni, Daniele Bruno, Fenizia Francesca, Molinari Enrico, Normanno Nicola, Manfrin Erminia, Vendraminelli Roberto, Colantuoni Vittorio
Abstract excerpt
BACKGROUND: Rhabdoid colorectal tumor (RCT) is a rare, highly aggressive neoplasm recurrent in elderly patients, commonly at the caecum. The molecular mechanisms underlying RCT pathogenesis remain poorly elucidated. The differential diagnosis is with the malignant rhabdoid tumors of infancy characterized by genetic inactivation of SMARCB1 (INI1) or deletions of chromosome 22q12 locus. MATERIALS AND METHODS: To...
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