Article
Human chromosome 9 can complement UV sensitivity of xeroderma pigmentosum group A cells.
Mutation research - 1 May 1990
Ishizaki K, Oshimura M, Sasaki M S, Nakamura Y, Ikenaga M
Abstract excerpt
A single human chromosome derived from normal human fibroblasts and tagged with the G418 resistance gene was transferred into SV40-transformed xeroderma pigmentosum group A (XP-A) cells via microcell fusion. When chromosome 1 or 12 was transferred, UV sensitivity of microcell hybrid cells was not changed. By contrast, after transferring chromosome 9, 7 of 11 recipient clones were as UV-resistant as normal human...
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