Article
Human chromosome 9 can complement UV sensitivity of xeroderma pigmentosum group A cells.
Mutation research - 1 May 1990
Ishizaki K, Oshimura M, Sasaki M S, Nakamura Y, Ikenaga M
Abstract excerpt
A single human chromosome derived from normal human fibroblasts and tagged with the G418 resistance gene was transferred into SV40-transformed xeroderma pigmentosum group A (XP-A) cells via microcell fusion. When chromosome 1 or 12 was transferred, UV sensitivity of microcell hybrid cells was not...
Topics
- Blotting, Southern
- Cell Survival
- Chromosomes, Human, Pair 9
- DNA
- DNA Repair
- Humans
- Hybrid Cells
- Mutation
- Ultraviolet Rays
- Xeroderma Pigmentosum
