Article
Association of XRCC1 gene polymorphisms with the survival and clinicopathological characteristics of gastric cancer.
DNA and cell biology - 1 Mar 2013
Zhang Yangmei, Wang Meilin, Gu Dongying, Wu Dongmei, Zhang Xiaojing, Gong Weida, Tan Yongfei, Zhou Jianwei, Wu Xiaomin, Tang Cuiju, Zhang Zhengdong, Chen Jinfei
Abstract excerpt
Polymorphisms of the DNA repair gene X-ray repair cross-complementing protein 1 (XRCC1) Arg194Trp, Arg280His, and Arg399Gln have been shown to alter the DNA repair activity and to be associated with genetic susceptibility to several types of cancer. We indentified genotypes of 944 surgically resected gastric cancer (GC) patients by the SNaPshot method to investigate the association of these polymorphisms with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
