Enabling high-throughput genotype-phenotype associations in the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) project as part of the Population Architecture using Genomics and Epidemiology (PAGE) study.

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Enabling high-throughput genotype-phenotype associations in the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) project as part of the Population Architecture using Genomics and Epidemiology (PAGE) study.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2013

Bush William S, Boston Jonathan, Pendergrass Sarah A, Dumitrescu Logan, Goodloe Robert, Brown-Gentry Kristin, Wilson Sarah, McClellan Bob, Torstenson Eric, Basford Melissa A, Spencer Kylee L, Ritchie Marylyn D, Crawford Dana C

Abstract excerpt

Genetic association studies have rapidly become a major tool for identifying the genetic basis of common human diseases. The advent of cost-effective genotyping coupled with large collections of samples linked to clinical outcomes and quantitative traits now make it possible to systematically characterize genotype-phenotype relationships in diverse populations and extensive datasets. To capitalize on these...

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PMID: 23424142
PMCID: PMC3579641

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