Article
Effect of cargo size and shape on the transport efficiency of the bacterial Tat translocase.
FEBS letters - 2 Apr 2013
Whitaker Neal, Bageshwar Umesh, Musser Siegfried M
Abstract excerpt
The Tat machinery translocates fully-folded and oligomeric substrates. The passage of large, bulky cargos across an ion-tight membrane suggests the need to match pore and cargo size, and therefore that Tat transport efficiency may depend on both cargo size and shape. A series of cargos of different sizes and shapes were generated using the natural Tat substrate pre-SufI as a base. Four (of 17) cargos transported...
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