Article
X-linked inhibitor of apoptosis single nucleotide polymorphisms and copy number variation are not risk factors for asthma.
Respirology (Carlton, Vic.) - 1 May 2013
Roscioli Eugene, Hamon Rhys, Ruffin Richard E, Zalewski Peter, Grant Janet, Lester Susan
Abstract excerpt
BACKGROUND AND OBJECTIVE: Aberrant apoptosis in asthma contributes to airway inflammation. Early apoptosis and fragility of airway epithelial cells and delayed apoptosis of inflammatory lymphocytes can cooperate to increase airway inflammation. In this study, single nucleotide polymorphisms (SNPs) and copy number variation (CNV) in the Baculoviral inhibitor of apoptosis protein repeat-containing 4 (BIRC4) gene...
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