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Article

A NIMA-related kinase, CNK4, regulates ciliary stability and length.

Molecular biology of the cell - 1 Mar 2016

Meng Dan, Pan Junmin

Abstract excerpt

NIMA-related kinases (Nrks or Neks) have emerged as key regulators of ciliogenesis. In human, mutations in Nek1 and Nek8 cause cilia-related disorders. The ciliary functions of Nrks are mostly revealed by genetic studies; however, the underlying mechanisms are not well understood. Here we show that a Chlamydomonas Nrk, CNK4, regulates ciliary stability and length. CNK4 is localized to the basal body region and...

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Identifiers

PMID: 26764095
DOI: 10.1091/mbc.E15-10-0707
PMCID: PMC4803309

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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