Article
Coding variants of TLR2 and TLR4 genes do not substantially contribute to prosthetic joint infection.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] - 1 May 2013
Mrazek Frantisek, Gallo Jiri, Stahelova Anna, Petrek Martin
Abstract excerpt
OBJECTIVE AND DESIGN: Prosthetic joint infection (PJI) is a severe complication of total joint arthroplasty (TJA). We conducted a genetic association study that investigated whether selected coding variants of the genes for Toll-like receptors (TLR)2 and TLR4 may contribute to genetic susceptibility for PJI. SUBJECTS AND METHODS: In total, 350 patients with TJA (98 with PJI/252 without PJI), and 189 unrelated...
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