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Article

[Toll-like receptor 2 R753Q polymorphisms are associated with an increased risk of infective endocarditis].

Revista espanola de cardiologia - 1 Nov 2011

Bustamante Juan, Tamayo Eduardo, Flórez Santiago, Telleria Juan J, Bustamante Elena, López Javier, San Román J Alberto, Alvarez F Javier

Abstract excerpt

The ability to respond to the ligands of toll-like receptors (TLR) could be affected by single nucleotide polymorphisms in TLR codifying genes. The influence of the polymorphisms TLR2 (R753Q, R677W), TLR4 (D299G, T399I) and CD14 (C-159T) was consecutively studied in 65 patients with infective endocarditis. The control group (n=66) consisted of healthy volunteers. All the polymorphisms were genotyped by means of...

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Identifiers

PMID: 21783307
DOI: 10.1016/j.recesp.2011.02.024

Genes

TLR2
TLR4

Variants

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