Article
Cytomegalovirus-specific T cells are primed early after cord blood transplant but fail to control virus in vivo.
Blood - 4 Apr 2013
McGoldrick Suzanne M, Bleakley Marie E, Guerrero Abraham, Turtle Cameron J, Yamamoto Tori N, Pereira Shalini E, Delaney Colleen S, Riddell Stanley R
Abstract excerpt
A disadvantage of umbilical cord blood transplantation (UCBT) is the delay in immune reconstitution, placing patients at increased risk for infections after transplant. Cytomegalovirus (CMV) in particular has been shown to cause significant morbidity in patients undergoing UCBT. Here, we comprehensively evaluate the development of CD4(+) and CD8(+) T-cell responses to CMV in a cohort of patients that underwent...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.