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Article

Schizophrenia genetic variants are not associated with intelligence.

Psychological medicine - 1 Dec 2013

van Scheltinga A F Terwisscha, Bakker S C, van Haren N E M, Derks E M, Buizer-Voskamp J E, Cahn W, Ripke S, Ophoff R A, Kahn R S

Abstract excerpt

BACKGROUND: Schizophrenia is associated with lower pre-morbid intelligence (IQ) in addition to (pre-morbid) cognitive decline. Both schizophrenia and IQ are highly heritable traits. Therefore, we hypothesized that genetic variants associated with schizophrenia, including copy number variants (CNVs) and a polygenic schizophrenia (risk) score (PSS), may influence intelligence. METHOD: IQ was estimated with the...

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Identifiers

PMID: 23410598
DOI: 10.1017/S0033291713000196
PMCID: PMC4743754

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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