Article
Light signal transduction pathway from flavin chromophore to the J alpha helix of Arabidopsis phototropin1.
Biophysical journal - 8 Apr 2009
Yamamoto Atsushi, Iwata Tatsuya, Sato Yoshiaki, Matsuoka Daisuke, Tokutomi Satoru, Kandori Hideki
Abstract excerpt
In the plant blue-light sensor phototropin, illumination of the chromophoric LOV domains causes activation of the serine/threonine kinase domain. Flavin mononucleotide (FMN) is a chromophore molecule in the two LOV domains (LOV1 and LOV2), but only LOV2 is responsible for kinase activation. Previous studies reported an important role of an additional helix connected to the C-terminal of LOV2 (Jalpha helix) for...
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