Article
Mathematical investigation of how oncogenic ras mutants promote ras signaling.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2012
Stites Edward C, Ravichandran Kodi S
Abstract excerpt
We have used a mathematical model of the Ras signaling network to link observable biochemical properties with cellular levels of RasGTP. Although there is abundant data characterizing Ras biochemistry, attributing specific changes in biochemical properties to observed phenotypes has been hindered...
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