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Article

Cannabinoid CB2 receptor gene (CNR2) polymorphism is associated with chronic childhood immune thrombocytopenia in Egypt.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Apr 2013

Mahmoud Gouda Heba, Mohamed Kamel Nermin R

Abstract excerpt

Immune thrombocytopenia (ITP) is a heterogeneous autoimmune disorder characterized by thrombocytopenia with or without mucocutaneous bleeding manifestations. ITP patients have significant defects in immune self-tolerance: autoreactive T-lymphocyte clones are capable of directly damaging platelets and possibly megakaryocytes and are likely to proliferate under the influence of Th lymphocytes. The CB2 receptor is...

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Source

Identifiers

PMID: 23406660
DOI: 10.1097/MBC.0b013e32835aba1d

Genes

CNR2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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