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Article

CNR2 functional variant (Q63R) influences childhood immune thrombocytopenic purpura.

Haematologica - 1 Dec 2011

Rossi Francesca, Mancusi Silvia, Bellini Giulia, Roberti Domenico, Punzo Francesca, Vetrella Simona, Matarese Sofia Maria Rosaria, Nobili Bruno, Maione Sabatino, Perrotta Silverio

Abstract excerpt

Immune thrombocytopenic purpura is an acquired autoimmune disorder that is the most common cause of thrombocytopenia in children. The endocannabinoid system is involved in immune regulation. We evaluated a common missense variant (CAA/CGG; Q63R) of the gene encoding the cannabinoid receptor type...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Mutation, Missense

Share to Purpura, Thrombocytopenic, Idiopathic

Share to Receptor, Cannabinoid, CB2

Source

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Identifiers

PMID: 21828121
DOI: 10.3324/haematol.2011.045732
PMCID: PMC3232275

Genes

CNR2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21828121-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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