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In vitro differentiation of human embryonic stem cells into ovarian follicle-like cells

12 Jun 2017

Abstract excerpt

Understanding the unique mechanisms of human oogenesis necessitates the development of an in vitro system of stem cell differentiation into oocytes. Specialized cell types and organoids have been derived from human pluripotent stem cells in vitro, but generating a human ovarian follicle remains a challenge. Here we report that human embryonic stem cells can be induced to differentiate into ovarian follicle-like...

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PMID: 28604658
DOI: 10.1038/ncomms15680

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