Genetic diversity and molecular epidemiology of multidrug-resistant Mycobacterium tuberculosis in Minas Gerais State, Brazil.

doi:10.1186/s12879-015-1057-y

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Article

Genetic diversity and molecular epidemiology of multidrug-resistant Mycobacterium tuberculosis in Minas Gerais State, Brazil.

BMC infectious diseases - 1 Aug 2015

Dantas Nayanne Gama Teixeira, Suffys Phillip Noel, Carvalho Wânia da Silva, Gomes Harrison Magdinier, de Almeida Isabela Neves, de Assis Lida Jouca, Augusto Claudio José, Gomgnimbou Michel Kireopori, Refregier Guislaine, Sola Christophe, de Miranda Silvana Spíndola

Abstract excerpt

BACKGROUND: We aimed to characterize the genetic diversity of drug-resistant Mycobacterium tuberculosis (MTb) clinical isolates and investigate the molecular epidemiology of multidrug-resistant (MDR) tuberculosis from Minas Gerais State, Brazil. METHODS: One hundred and four MTb clinical isolates were assessed by IS6110-RFLP, 24-locus mycobacterial interspersed repetitive units variable-number tandem repeats...

Topics

Alleles
Antitubercular Agents
Bacterial Proteins
Brazil
Cluster Analysis
DNA, Bacterial
DNA-Directed RNA Polymerases
Genetic Variation
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Isoniazid

Minisatellite Repeats

Mycobacterium tuberculosis

Phylogeny

Polymerase Chain Reaction

Polymorphism, Genetic

Rifampin

Tuberculosis, Multidrug-Resistant

Source

Open in PubMed Open full text

Identifiers

PMID: 26231661
DOI: 10.1186/s12879-015-1057-y
PMCID: PMC4521345

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-26231661-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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