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Article

MRI analysis of cerebellar and vestibular developmental phenotypes in Gbx2 conditional knockout mice.

Magnetic resonance in medicine - 1 Dec 2013

Szulc Kamila U, Nieman Brian J, Houston Edward J, Bartelle Benjamin B, Lerch Jason P, Joyner Alexandra L, Turnbull Daniel H

Abstract excerpt

PURPOSE: Our aim in this study was to apply three-dimensional MRI methods to analyze early postnatal morphological phenotypes in a Gbx2 conditional knockout (Gbx2-CKO) mouse that has variable midline deletions in the central cerebellum, reminiscent of many human cerebellar hypoplasia syndromes. METHODS: In vivo three-dimensional manganese-enhanced MRI at 100-µm isotropic resolution was used to visualize mouse...

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Identifiers

PMID: 23400959
DOI: 10.1002/mrm.24597
PMCID: PMC3657598

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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