Article

Olfactory bulb anomalies in KBG syndrome mouse model and patients

2023-09-08

Abstract excerpt

<title>Abstract</title> <p><italic>ANKRD11 </italic>(Ankyrin Repeat Domain 11) is a chromatin regulator and the only gene associated with KBG syndrome, a rare neurodevelopmental disorder. We have previously shown that Ankrd11 regulates murine embryonic cortical neurogenesis. Here, we show a novel olfactory bulb phenotype in a KBG syndrome mouse model and two diagnosed patients. Conditional knockout of <italic>Ank...

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Literature Corpus work: de8b7db7-96d3-5bf7-a962-476d92122dd8
DOI: 10.21203/rs.3.rs-3314982/v1

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