Comparative proteomic analysis of two Entamoeba histolytica strains with different virulence phenotypes identifies peroxiredoxin as an important component of amoebic virulence

Abstract excerpt

Entamoeba histolytica is a protozoan intestinal parasite that causes amoebic colitis and amoebic liver abscess. To identify virulence factors of E. histolytica, we first defined the phenotypes of two E. histolytica strains, HM-1:IMSS, the prototype virulent strain, and E. histolytica Rahman, a strain that was reportedly less virulent than HM-1:IMSS. We found that compared with HM-1:IMSS, Rahman has a defect in...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Amoebic Infections and Treatments
• Share to Heme Oxygenase-1 and Carbon Monoxide
• Share to Parasitic Infections and Diagnostics