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Article

Direct detection of beta thalassemic mutations: use of biotin-labelled allele specific probes.

American journal of hematology - 1 Jun 1990

Hendy J G, Cauchi M N

Abstract excerpt

Mutations at positions beta IVS1-6, beta IVS1-110, and beta 39 of the beta globin gene are responsible for the three most common thalassemic genes in the Mediterranean population. The polymerase chain reaction (PCR) was employed to amplify a 536 base pair segment surrounding this region. Nonradioactive labelling of an oligonucleotide probe, specific for the beta IVS1-110 mutation, was achieved by incorporation of...

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Identifiers

PMID: 2339680
DOI: 10.1002/ajh.2830340213

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Direct detection of beta thalassemic mutations: use of biotin-labelled allele specific probes.PMID 2339680Read ↗

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