Beta-thalassemia mutations in Singapore--a strategy for prenatal diagnosis.

doi:10.1007/BF00201598

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Article

Beta-thalassemia mutations in Singapore--a strategy for prenatal diagnosis.

Human genetics - 1 Oct 1994

Ng I S, Ong J B, Tan C L, Law H Y

Abstract excerpt

The strategy for early prenatal diagnosis of beta-thalassemia in Singapore by direct detection of the mutant beta-globin gene requires the spectrum of mutations producing the disorder in this population to be characterized. We analyzed 134 beta-thalassemia alleles from Singapore by specific oligo...

Topics

Alleles
Base Sequence
Chromosome Deletion
Genotype
Humans
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
Prenatal Diagnosis
Singapore
beta-Thalassemia

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