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Article

Pathway-based analysis of primary biliary cirrhosis genome-wide association studies.

Genes and immunity - 1 Apr 2013

Kar S P, Seldin M F, Chen W, Lu E, Hirschfield G M, Invernizzi P, Heathcote J, Cusi D, Gershwin M E, Siminovitch K A, Amos C I

Abstract excerpt

Genome-wide association studies (GWAS) have successfully identified several loci associated with primary biliary cirrhosis (PBC) risk. Pathway analysis complements conventional GWAS analysis. We applied the recently developed linear combination test for pathways to datasets drawn from independent PBC GWAS in Italian and Canadian subjects. Of the Kyoto Encyclopedia of Genes and Genomes and BioCarta pathways...

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Identifiers

PMID: 23392275
DOI: 10.1038/gene.2013.1
PMCID: PMC3780793

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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