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Article

Inhibition of TTR aggregation-induced cell death--a new role for serum amyloid P component.

PloS one - 1 Jan 2013

Andersson Karin, Pokrzywa Malgorzata, Dacklin Ingrid, Lundgren Erik

Abstract excerpt

BACKGROUND: Serum amyloid P component (SAP) is a glycoprotein that is universally found associated with different types of amyloid deposits. It has been suggested that it stabilizes amyloid fibrils and therefore protects them from proteolytic degradation. METHODOLOGY/PRINCIPAL FINDINGS: In this paper, we show that SAP binds not only to mature amyloid fibrils but also to early aggregates of amyloidogenic mutants...

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Source

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Identifiers

PMID: 23390551
DOI: 10.1371/journal.pone.0055766
PMCID: PMC3563535

Genes

TTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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