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Article

Suppression of hepcidin expression and iron overload mediate Salmonella susceptibility in ankyrin 1 ENU-induced mutant.

PloS one - 1 Jan 2013

Yuki Kyoko E, Eva Megan M, Richer Etienne, Chung Dudley, Paquet Marilène, Cellier Mathieu, Canonne-Hergaux François, Vaulont Sophie, Vidal Silvia M, Malo Danielle

Abstract excerpt

Salmonella, a ubiquitous Gram-negative intracellular bacterium, is a food borne pathogen that infects a broad range of hosts. Infection with Salmonella Typhimurium in mice is a broadly recognized experimental model resembling typhoid fever in humans. Using a N-ethyl-N-nitrosurea (ENU) mutagenesis recessive screen, we report the identification of Ity16 (Immunity to Typhimurium locus 16), a locus responsible for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23390527
DOI: 10.1371/journal.pone.0055331
PMCID: PMC3563626

Genes

HAMP
ANK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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