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Article

The detection of KIT mutations in acute myeloid leukemia.

Einstein (Sao Paulo, Brazil) - 1 Jan 2000

Machado Luis Eduardo Silva, Pinho João Renato Rebello, Sitnik Roberta, Muto Nair Hideko, Velloso Elvira Deolinda Rodrigues Pereira, Petroni Roberta Cardoso, Campregher Paulo Vidal

Abstract excerpt

OBJECTIVE: This study describes a new method used in the clinical laboratory at Hospital Israelita Albert Einstein to detect mutations in exons 8 and 17 of the KIT gene in patients with acute myeloid leukemia. METHODS: Genomic DNA extraction was performed on 54 samples of peripheral blood or bone marrow from patients with acute myeloid leukemia. The extracted DNA was amplified by polymerase chain reaction and...

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Topics

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Share to Electrophoresis, Capillary
Share to Exons

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukemia, Myeloid, Acute

Share to Polymorphism, Single-Stranded Conformational

Share to Proto-Oncogene Proteins c-kit

Share to Reproducibility of Results

Share to Sensitivity and Specificity

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 23386005
DOI: 10.1590/s1679-45082012000300005

Genes

KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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