Article
KIT mutation detection in Tunisian patients with newly diagnosed myelogenous leukemia: prevalence and prognostic significance.
Cancer genetics - 1 Sept 2012
Ouerhani Slah, Gharbi Hanen, Menif Samia, Safra Ines, Douzi Kais, Abbes Salem
Abstract excerpt
The KIT gene encodes a class III tyrosine kinase receptor in which specific somatic mutations have been found to be associated with many diseases. In this work, we investigated the prevalence of KIT mutations in patients with chronic and acute myelogenous leukemia (CML and AML) and their prognostic significance. A total of 157 subjects were included in the present study (84 patients with CML, 33 with AML, and 40...
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