Article
Reduced genome size of Helicobacter pylori originating from East Asia.
World journal of gastroenterology - 21 May 2014
Dong Quan-Jiang, Wang Li-Li, Tian Zi-Bing, Yu Xin-Jun, Jia Sheng-Jiao, Xuan Shi-Ying
Abstract excerpt
Helicobacter pylori (H. pylori), a major pathogen colonizing the human stomach, shows great genetic variation. Comparative analysis of strains from different H. pylori populations revealed that the genome size of strains from East Asia decreased to 1.60 Mbp, which is significantly smaller than that from Europe or Africa. In parallel with the genome reduction, the number of protein coding genes was decreased, and...
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