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Article

Evolution in an oncogenic bacterial species with extreme genome plasticity: Helicobacter pylori East Asian genomes.

BMC microbiology - 16 May 2011

Kawai Mikihiko, Furuta Yoshikazu, Yahara Koji, Tsuru Takeshi, Oshima Kenshiro, Handa Naofumi, Takahashi Noriko, Yoshida Masaru, Azuma Takeshi, Hattori Masahira, Uchiyama Ikuo, Kobayashi Ichizo

Abstract excerpt

BACKGROUND: The genome of Helicobacter pylori, an oncogenic bacterium in the human stomach, rapidly evolves and shows wide geographical divergence. The high incidence of stomach cancer in East Asia might be related to bacterial genotype. We used newly developed comparative methods to follow the evolution of East Asian H. pylori genomes using 20 complete genome sequences from Japanese, Korean, Amerind, European,...

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Identifiers

PMID: 21575176
DOI: 10.1186/1471-2180-11-104
PMCID: PMC3120642

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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