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Article

Genetic variations in the KCNJ5 gene in primary aldosteronism patients from Xinjiang, China.

PloS one - 1 Jan 2013

Li Nan-Fang, Li Hong-Jian, Zhang De-Lian, Zhang Ju-Hong, Yao Xiao-Guang, Wang Hong-Mei, Abulikemu Suofeiya, Zhou Ke-Ming, Zhang Xiang-Yang

Abstract excerpt

BACKGROUND: Primary aldosteronism (PA) is the most common endocrine form of secondary hypertension, and one of the most common subtypes of sporadic PA is aldosterone-producing adenoma (APA). Recently, two somatic mutations of the KCNJ5 gene were implicated in APA, and two germline mutations were associated with familial hyperaldosteronism III. OBJECTIVES: This case-control study was designed to investigate the...

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Identifiers

PMID: 23382865
DOI: 10.1371/journal.pone.0054051
PMCID: PMC3561325

Genes

KCNJ5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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