Unravelling the Genetic Basis of Primary Aldosteronism.

Abstract excerpt

Primary aldosteronism (PA), a condition characterized by autonomous aldosterone hypersecretion, constitutes the most common cause of secondary hypertension. Over the last decade, major breakthroughs have been made in the field of genetics underpinning PA. The advent and wide application of Next Generation Sequencing (NGS) technology led to the identification of several somatic and germline mutations associated...

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• Aldosterone
• Germ-Line Mutation
• High-Throughput Nucleotide Sequencing
• Hyperaldosteronism
• Hypertension