Article
Rapid selection of Plasmodium falciparum chloroquine resistance transporter gene and multidrug resistance gene-1 haplotypes associated with past chloroquine and present artemether-lumefantrine use in Inhambane District, southern Mozambique.
The American journal of tropical medicine and hygiene - 1 Mar 2013
Thomsen Thomas T, Madsen Laura B, Hansson Helle H, Tomás Elsa V E, Charlwood Derek, Bygbjerg Ib C, Alifrangis Michael
Abstract excerpt
Chloroquine (CQ) use in Mozambique was stopped in 2002 and artemether-lumefantrine (AL) was implemented in 2008. In light of no use of CQ and extensive use of AL, we determined the frequency of molecular markers of Plasmodium falciparum drug resistance/tolerance to CQ and AL in persons living in...
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