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Article

Efficacy of artemether-lumefantrine in treatment of malaria among under-fives and prevalence of drug resistance markers in Igombe-Mwanza, north-western Tanzania.

Malaria journal - 27 Feb 2012

Kamugisha Erasmus, Jing Sun, Minde Mercy, Kataraihya Johaness, Kongola Gilbert, Kironde Fred, Swedberg Göte

Abstract excerpt

BACKGROUND: Drug resistance to anti-malarials is a major public health problem worldwide. This study aimed at establishing the efficacy of artemether-lumefantrine (ACT) in Igombe-Mwanza, north-western Tanzania after a few years of ACT use, and establish the prevalence of mutations in key targets for artemisinin, chloroquine and sulphadoxine/pyrimetamine (SP) drugs. METHODS: A prospective single cohort study was...

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Identifiers

PMID: 22369089
DOI: 10.1186/1475-2875-11-58
PMCID: PMC3305412

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