Article
Efficacy of artemether-lumefantrine in treatment of malaria among under-fives and prevalence of drug resistance markers in Igombe-Mwanza, north-western Tanzania.
Malaria journal - 27 Feb 2012
Kamugisha Erasmus, Jing Sun, Minde Mercy, Kataraihya Johaness, Kongola Gilbert, Kironde Fred, Swedberg Göte
Abstract excerpt
BACKGROUND: Drug resistance to anti-malarials is a major public health problem worldwide. This study aimed at establishing the efficacy of artemether-lumefantrine (ACT) in Igombe-Mwanza, north-western Tanzania after a few years of ACT use, and establish the prevalence of mutations in key targets for artemisinin, chloroquine and sulphadoxine/pyrimetamine (SP) drugs. METHODS: A prospective single cohort study was...
Topics
- Antigens, Protozoan
- Antimalarials
- Artemether, Lumefantrine Drug Combination
- Artemisinins
- Blood
- Child, Preschool
- Cohort Studies
- DNA Fingerprinting
- DNA, Protozoan
- Drug Combinations
- Drug Resistance
- Ethanolamines
- Female