Article
Surveillance of artemether-lumefantrine associated Plasmodium falciparum multidrug resistance protein-1 gene polymorphisms in Tanzania.
Malaria journal - 9 Jul 2014
Kavishe Reginald A, Paulo Petro, Kaaya Robert D, Kalinga Akili, van Zwetselaar Marco, Chilongola Jaffu, Roper Cally, Alifrangis Michael
Abstract excerpt
BACKGROUND: Resistance to anti-malarials is a major public health problem worldwide. After deployment of artemisinin-based combination therapy (ACT) there have been reports of reduced sensitivity to ACT by malaria parasites in South-East Asia. In Tanzania, artemether-lumefantrine (ALu) is the recommended first-line drug in treatment of uncomplicated malaria. This study surveyed the distribution of the Plasmodium...
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