Article
Temporal trends of molecular markers associated with artemether-lumefantrine tolerance/resistance in Bagamoyo district, Tanzania.
Malaria journal - 18 Mar 2013
Malmberg Maja, Ngasala Billy, Ferreira Pedro E, Larsson Erik, Jovel Irina, Hjalmarsson Angelica, Petzold Max, Premji Zul, Gil José P, Björkman Anders, Mårtensson Andreas
Abstract excerpt
BACKGROUND: Development and spread of Plasmodium falciparum resistance to artemisinin-based combination therapy (ACT) constitutes a major threat to recent global malaria control achievements. Surveillance of molecular markers could act as an early warning system of ACT-resistance before clinical treatment failures are apparent. The aim of this study was to analyse temporal trends of established genotypes...
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