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Article

Genetic variation in RNASEL associated with prostate cancer risk and progression.

Carcinogenesis - 1 Sept 2010

Meyer Mara S, Penney Kathryn L, Stark Jennifer R, Schumacher Fredrick R, Sesso Howard D, Loda Massimo, Fiorentino Michelangelo, Finn Stephen, Flavin Richard J, Kurth Tobias, Price Alkes L, Giovannucci Edward L, Fall Katja, Stampfer Meir J, Ma Jing, Mucci Lorelei A

Abstract excerpt

Variation in genes contributing to the host immune response may mediate the relationship between inflammation and prostate carcinogenesis. RNASEL at chromosome 1q25 encodes ribonuclease L, part of the interferon-mediated immune response to viral infection. We therefore investigated the association between variation in RNASEL and prostate cancer risk and progression in a study of 1286 cases and 1264 controls...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20576793
DOI: 10.1093/carcin/bgq132
PMCID: PMC2930803

Genes

RNASEL
CRP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic variation in RNASEL associated with prostate cancer risk and progression.PMID 20576793Read ↗

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Predictive value in the analysis of RNASEL genotypes in relation to prostate cancer.Semantic proximity Read ↗

Functional and Structural Consequences of Damaging Single Nucleotide Polymorphisms in Human Prostate Cancer Predisposition Gene RNASEL.Semantic proximity Read ↗

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