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Article

Identification of somatic and germline mutations using whole exome sequencing of congenital acute lymphoblastic leukemia.

BMC cancer - 4 Feb 2013

Chang Vivian Y, Basso Giuseppe, Sakamoto Kathleen M, Nelson Stanley F

Abstract excerpt

BACKGROUND: Acute lymphoblastic leukemia (ALL) diagnosed within the first month of life is classified as congenital ALL and has a significantly worse outcome than ALL diagnosed in older children. This suggests that congenital ALL is a biologically different disease, and thus may be caused by a distinct set of mutations. To understand the somatic and germline mutations contributing to congenital ALL, the...

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Share to Databases, Genetic
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Share to Genome, Human

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Germ-Line Mutation

Share to Infant, Newborn

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Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

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Source

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Identifiers

PMID: 23379653
DOI: 10.1186/1471-2407-13-55
PMCID: PMC3573941

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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