Article
The highly conserved LAMMER/CLK2 protein kinases prevent germ cell overproliferation in Drosophila.
Developmental biology - 15 Apr 2013
Zhao Shaowei, Chen Di, Geng Qing, Wang Zhaohui
Abstract excerpt
Germ cells undergo proper mitotic amplification before entering meiosis. The mitosis/meiosis switch drives the germ cells to leave the potential stem cell pool and become terminally differentiated. This important process is tightly controlled in the spermatogenesis of all animals. However, a unifying mechanism has yet to be unraveled. Drosophila spermatogenesis is an ideal system to dissect the regulatory program...
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