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Article

Complement factor B polymorphism and the phenotype of early age-related macular degeneration.

Ophthalmic genetics - 1 Mar 2014

Mantel Irmela, Ambresin Aude, Moetteli Leila, Droz Ivaine, Roduit Raphaël, Munier Francis L, Schorderet Daniel F

Abstract excerpt

PURPOSE: Age-related macular degeneration (AMD) has been associated with a number of polymorphisms in genes in the complement pathway. We examined the potential genotype-phenotype correlation of complement factor B (CFB) (R32Q) polymorphisms in Caucasian patients with AMD. METHODS: Data from a Central European cohort of 349 patients with early AMD in at least one eye were analyzed for potential associations of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23373431
DOI: 10.3109/13816810.2013.766217

Genes

CFB
ARMS2
CFH

Variants

rs641153
rs641153

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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