Article
In vitro analysis of bone phenotypes in Col1a1 and Jagged1 mutant mice using a standardized osteoblast cell culture system.
Journal of bone and mineral metabolism - 1 May 2013
Thiele Frank, Cohrs Christian M, Przemeck Gerhard K H, Wurst Wolfgang, Fuchs Helmut, Hrabé de Angelis Martin
Abstract excerpt
The mouse is a valuable model organism for studying bone biology and for unravelling pathological processes in skeletal disorders. In vivo methods like X-ray analysis, DXA measurements, pQCT and μCT are available to investigate the bone phenotype of mutant mice. However, the descriptive nature of...
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