Article
Is there any association between the Ser326Cys polymorphism of the 8-oxoguanine glycosylase 1 (OGG1) gene and risk of colon polyp and abnormal glucose tolerance in acromegaly patients?
Genetic testing and molecular biomarkers - 1 Apr 2013
Zengi Ayhan, Karadeniz Muammer, Cetintas Vildan Bozok, Harman Ece, Tetik Aslı, Orman Mehmet, Eroglu Zuhal, Cetinkalp Sevki, Ozgen Ahmet Gokhan, Saygili Fusun, Yilmaz Candeger
Abstract excerpt
AIM: Evidence arising from experimental studies indicates an association between increased levels of the growth hormone/insulin-like growth factor 1 and oxidative stress. The association of the Ser326Cys polymorphism in the 8-oxoguanine glycosylase (OGG1) gene with a colon carcinoma and diabetes mellitus has been examined. The aim of the study was to compare the genotypic distribution of OGG1 Ser326Cys between...
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