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Article

MTHFR C677T polymorphism, folate status and colon cancer risk in acromegalic patients.

Pituitary - 1 Jun 2014

Torre Maria Luisa, Russo Giuseppina T, Ragonese Marta, Giandalia Annalisa, De Menis Ernesto, Arnaldi Giorgio, Alibrandi Angela, Buda Carmelo, Romanello Giovanni, Romeo Elisabetta L, Cucinotta Domenico, Trimarchi Francesco, Cannavo Salvatore

Abstract excerpt

BACKGROUND: Acromegalic patients have a higher risk of developing colorectal tumours (CRT). The common C677T polymorphism in methylenetetrahydrofolate reductase (MTHFR) gene is a well-documented CRT risk factor in the general population, but its role in acromegaly has never been examined. PURPOSE: We investigated the influence of MTHFR C677T polymorphism, folate status and other lifestyle, nutritional and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23807201
DOI: 10.1007/s11102-013-0499-8

Genes

MTHFR

Variants

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