Interaction of RNA polymerase I transcription factors with a promoter in the nontranscribed spacer of rat ribosomal DNA.

doi:10.1093/nar/18.7.1677

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Article

Interaction of RNA polymerase I transcription factors with a promoter in the nontranscribed spacer of rat ribosomal DNA.

Nucleic acids research - 11 Apr 1990

Smith S D, Oriahi E, Yang-Yen H F, Xie W Q, Chen C, Rothblum L I

Abstract excerpt

The spacer promoter of the rat rDNA repeat consists of two functional domains: a core (proximal) element that is sufficient for transcription in vitro, and an upstream (distal) promoter element that increases the efficiency of transcription. Two of the transcription factors that interact with the 45S promoter also interact with the spacer promoter. Rat SL-1, is required for transcription of the spacer promoter by...

Topics

Animals
Base Sequence
Cell Nucleus
Chromosome Deletion
Cloning, Molecular
DNA, Ribosomal
HeLa Cells
Humans
Liver Neoplasms, Experimental
Molecular Sequence Data
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Promoter Regions, Genetic

RNA Polymerase I

Rats

Restriction Mapping

Templates, Genetic

Transcription Factors

Transcription, Genetic

Source

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Identifiers

PMID: 2336355
DOI: 10.1093/nar/18.7.1677
PMCID: PMC330583

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2336355-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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