Article
Sequence-specific binding of a transcription factor TFID to the promoter region of mouse ribosomal RNA gene.
The Journal of biological chemistry - 15 Aug 1990
Tanaka N, Kato H, Ishikawa Y, Hisatake K, Tashiro K, Kominami R, Muramatsu M
Abstract excerpt
The binding sites of TFID, a species-dependent transcription factor, on the mouse ribosomal RNA gene (rDNA) have been analyzed by DNase I footprinting using partially purified TFID. The region -12 to -140 spanning over the upper half of the core promoter (-12 to -40) and an upstream sequence (-40 to -140) was protected. Human fraction D could not protect corresponding regions of mouse rDNA indicating that the...
Topics
- Animals
- Base Sequence
- Binding Sites
- Binding, Competitive
- Chromatography, Affinity
- Chromatography, Ion Exchange
- Chromosome Deletion
- DNA, Ribosomal
- Deoxyribonuclease I
- Humans
- Mice