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Article

Genotype-based association analysis using discordant pairs: a penetrance odds ratio approach.

Annals of human genetics - 1 Mar 2013

Grover Vaneeta K, Cole David E C, Hamilton David C

Abstract excerpt

Genotypic counts of paired relatives discordant for a complex late-onset disease are often used to test for genetic association. The power of the various statistical test options, when data on covariates are unavailable, has been the focus of recent research. Comparison of the Cochran-Armitage, Bhapkar, and McNemar tests indicates that none is superior to the others in all cases. Using an alternative approach, we...

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PMID: 23362881
DOI: 10.1111/ahg.12002

Genes

CFH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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